abstract：:Surgically resected subretinal proliferative tissue (SRP) in proliferative vitreoretinopathy was examined by morphological and immunohistochemical methods. Membranous and strand-like SRPs were observed. Membranous SRP (4 cases) consisted of retinal pigment epithelial cells (RPEs) and a thin layer of extracellular mate...

journal_title：Japanese journal of ophthalmology

authors： Okada M,Ogino N,Matsumura M,Honda Y,Nagai Y

更新日期：1992-01-01 00:00:00

abstract：:Lymphatic sinus-like structures were demonstrated in the choroid of the monkey eye by transmission and scanning electron microscopy. These lymphatic sinus-like structures were lined by fibroblast-like cells with large intercellular gaps. When the specimens were viewed by scanning electron microscopy, the surface morph...

journal_title：Japanese journal of ophthalmology

authors： Sugita A,Inokuchi T

更新日期：1992-01-01 00:00:00

abstract：:Silicone oil was injected into the eyes of 28 rabbits. Utilizing the specific affinity of osmium tetroxide for lipids, the pathological features and histochemical localization of silicone oil within the retina were studied. This osmium tetroxide technique makes it possible to identify the presence of silicone oil part...

journal_title：Japanese journal of ophthalmology

authors： Shikishima K,Ohki K,Machi N,Sano Y

更新日期：1992-01-01 00:00:00

abstract：:S-antigen (S-Ag), a well characterized 45-kDa protein in the photoreceptor cells, induces predominantly T-cell-mediated autoimmune uveitis when injected into experimental animals. Recently, we have shown that native histone H3 protein derived from yeast (Saccharomyces cerevisiae), or a synthetic peptide that is homolo...

journal_title：Japanese journal of ophthalmology

authors： Singh VK,Usukura J,Shinohara T

更新日期：1992-01-01 00:00:00

abstract：:It has been reported that keratocytes endocytose foreign particles both in vitro and in vivo, suggesting the active participation of keratocytes in corneal wound healing and host defense mechanism. To understand the cellular response and the fate of engulfed foreign particles, we investigated the changes in the lysoso...

journal_title：Japanese journal of ophthalmology

authors： Mishima H,Ueda A,Nishida T,Otori T

更新日期：1992-01-01 00:00:00

abstract：:A case of bilateral retinoblastoma affecting both of a pair of dizygotic twins was reported. To our knowledge, there has been only one previous report of dizygotic twins, both affected, with this disease. The present twins had no family history of retinoblastoma. They were born prematurely as extremely low birth weigh...

journal_title：Japanese journal of ophthalmology

authors： Amino K,Ichioka I,Ichioka H,Matsubara K,Lin YW,Ohta S

更新日期：1992-01-01 00:00:00

abstract：:Two siblings with Usher syndrome had optic disc mulberry tumors that were photographically documented over a 5-year period. During this period, growth of these tumors was demonstrated. These lesions were reported histologically to be drusen. The existence of presumed optic disc drusen in siblings with Usher syndrome m...

journal_title：Japanese journal of ophthalmology

authors： Shiono T,Noro M,Tamai M

更新日期：1991-01-01 00:00:00

abstract：:An animal model was used to evaluate the influence of residual lens cortex on postoperative inflammation and cellular deposits on intraocular lenses (IOLs). Eighteen New Zealand white rabbits underwent bilateral endocapsular phacoemulsification with placement of a one-piece polymethylmethacrylate (PMMA) IOL in the cap...

journal_title：Japanese journal of ophthalmology

authors： Tamura M,Monson MC,Davis B,Mamalis N

更新日期：1991-01-01 00:00:00

abstract：:The effects of four commercially available irrigating solutions on the spreading of rabbit corneal endothelial cells on various extracellular matrices were studied. Cultured rabbit corneal endothelial cells, suspended in one of the following intraocular irrigating solutions, Opeguard MA, BSS, BSS Plus, lactated Ringer...

journal_title：Japanese journal of ophthalmology

authors： Nishida T,Otori T

更新日期：1991-01-01 00:00:00

abstract：:We studied the inhibitory effects of chicken egg white ovomacroglobulin, a broad-spectrum protease inhibitor, and a synthetic protease inhibitory peptide, Bz-GFR-O-mercaptoanilide, on the growth of two strains of Serratia marcescens in a synthetic medium. The growth of the virulent protease-producing strain, S. marces...

journal_title：Japanese journal of ophthalmology

authors： Miyagawa S,Matsumoto K,Kamata R,Okamura R,Maeda H

更新日期：1991-01-01 00:00:00

abstract：:A new in vitro model to evaluate the corneal endothelial wound-healing process was developed. Confluent monolayer cell sheets of either rabbit or bovine corneal endothelial cells were cultured on cover slips, the surface of which had been precoated with hydroxyethyl methacrylate (HEMA) except for the 8 mm-diameter are...

journal_title：Japanese journal of ophthalmology

authors： Miyata K,Murao M,Sawa M,Tanishima T

更新日期：1990-01-01 00:00:00

abstract：:A locally aggressive nonteratoid intraocular medulloepithelioma occurring in a two-year-old boy was studied by electron microscopy. For comparison the primitive pars plana region was examined in human fetal eyes obtained at 16, 18 and 22 weeks of gestation. The tumour was polymorphic with neural, intermediate and epit...

journal_title：Japanese journal of ophthalmology

authors： Wakakura M,Lee WR

更新日期：1990-01-01 00:00:00

abstract：:A computerized digital image analysis system was developed to evaluate the retinal nerve fiber layer (RNFL) by red-free fundus photography. The image intensity of the RNFL was computed for 30 degrees between the disc and macula. Thirty early open-angle glaucoma patients and 30 normal age-matched subjects were examined...

journal_title：Japanese journal of ophthalmology

authors： Yamazaki Y,Miyazawa T,Yamada H

更新日期：1990-01-01 00:00:00

abstract：:The complexity of visual field result evaluation has increased with the advent of automated perimetry. This in turn makes software assistance such as provided by the new Octosmart program interesting and desirable. Its accuracy and reliability in visual field evaluation must be tested, though, and the testing methodol...

journal_title：Japanese journal of ophthalmology

authors： Hirsbrunner HP,Fankhauser F,Funkhouser AT,Jenni A

更新日期：1990-01-01 00:00:00

abstract：:The effect of 3,3'-iminodipropionitrile (IDPN) on experimental intravitreal proliferation in albino rabbits was studied by light and electron microscopy. About 2.5 x 10(5) tissue cultured fibroblasts were injected into the vitreous cavity of albino rabbits. Immediately after the injection, phosphate-buffered solution ...

journal_title：Japanese journal of ophthalmology

authors： Akiyama K

更新日期：1990-01-01 00:00:00

abstract：:Changes in the distribution pattern of chloride ions were studied in the embryonic chicken retinal pigment epithelium (RPE), chloride ions being deposited as silver chloride (AgCl) in the RPE and observed by electron microscope. Before the 7th day after fertilization, the chloride ions did not accumulate anywhere in t...

journal_title：Japanese journal of ophthalmology

authors： Yamashita H,Yamamoto T

更新日期：1990-01-01 00:00:00

abstract：:Medical histories with emphasis on malignant disease were obtained on 1,269 first and second degree relatives of 93 probands with retinoblastoma and on 671 first and second degree relatives of 50 age-matched control children. The number of nonocular malignancies expected to occur in first and second degree relatives o...

journal_title：Japanese journal of ophthalmology

authors： Cohen MS,Augsburger JJ,Shields JA,Amsel J,Felberg NT

更新日期：1989-01-01 00:00:00

abstract：:Characteristics of the distribution of cytoskeletal and contractile elements in cultured human trabecular cells were studied using the immunofluorescence method. Actin microfilaments exhibited stress fiber images which were observed throughout the cell body in a parallel pattern and were concentrated in the cell perip...

journal_title：Japanese journal of ophthalmology

authors： Tamura M,Iwamoto Y,Nakatsuka K,Yamanouchi U

更新日期：1989-01-01 00:00:00

abstract：:Astrocytes were cultured from the cerebral cortices of newborn rabbits and were so confirmed by staining of the glial fibrillary acidic protein (GFAP). In Experiment I, the astrocytes of newborn rabbits of both sexes from one mother were pooled and suspended in a culture medium, and approximately 1-2 X 10(4) cells wer...

journal_title：Japanese journal of ophthalmology

authors： Mishima N,Yamashita H,Ishii Y,Hori S

更新日期：1989-01-01 00:00:00

abstract：:The exfoliation syndrome is thought to be a very rare disease in China. The clinical features of 11 patients with pseudoexfoliation (PE) and the histopathologic changes in specimens affected by PE were studied. The loss of pigment at the pupillary ruff and the dense pigmentation on the trabecular meshwork were the ear...

journal_title：Japanese journal of ophthalmology

authors： Ye TC,Mao WS,Zhang J

更新日期：1989-01-01 00:00:00

abstract：:Management of intraocular tumors, specifically uveal melanoma, is a matter of controversy. The treatment of these ocular neoplasms varies from observation to enucleation, irradiation (cobalt plaque and proton-helium particle) and eye wall resection. Over the last 18 years, we have developed two techniques for surgical...

journal_title：Japanese journal of ophthalmology

authors： Peyman GA,Gremillion CM

更新日期：1989-01-01 00:00:00

abstract：:The effects of three sulfhydryl agents on the cytoskeletal systems of cultured human trabecular cells were examined by the immunofluorescence method. Incubation with iodoacetamide or N-ethyl maleimide (10(-6) M, 10(-5) M, and 10(-4) M) caused a marked alteration on the actin and microtubule organization, but had littl...

journal_title：Japanese journal of ophthalmology

authors： Iwamoto Y,Tamura M,Nakatsuka K,Yamanouchi U

更新日期：1989-01-01 00:00:00

abstract：:In this report, membranes removed during vitrectomy were observed by various methods of electron microscopy to determine their three-dimensional structure and the mechanism of the contraction of preretinal membranes. The vitreous side surface of the preretinal membranes was covered by two types of flat cells, cells wi...

journal_title：Japanese journal of ophthalmology

authors： Yamamoto T,Yamashita H,Hori S

更新日期：1989-01-01 00:00:00

abstract：:In an attempt to study the effect of change in the intraocular pressure (IOP) on the status of the vitreous-aqueous interface, the effect of topical bunazosin was studied in the rabbit eye using the new Johnson-Maurice method. This entails an intravitreal injection of FITC-dextran and measurements of its concentration...

journal_title：Japanese journal of ophthalmology

authors： Sugiura Y,Araie M

更新日期：1989-01-01 00:00:00

abstract：:The effect of pertussis toxin (PT) on experimental autoimmune uveoretinitis (EAU) induced by immunization with S-antigen was examined in rats. Intravenous administration of PT (2 micrograms/rat) initiated the development of EAU in rats that had been made resistant to the induction of EAU by immunization with S-antigen...

journal_title：Japanese journal of ophthalmology

authors： Suzuki I,Takahashi S,Fujii Y,Fuyama S,Arai S

更新日期：1989-01-01 00:00:00

abstract：:Retinol-binding protein (RBP) is a plasma protein with a molecular weight of 21,000 synthesized in the hepatocytes, binding with retinol (vitamin A), and transporting retinol to peripheral tissues. Keratomalacia is caused by a deficiency of vitamin A itself and/or protein-calorie malnutrition. In the latter condition,...

journal_title：Japanese journal of ophthalmology

authors： Matsuo T,Matsuo N,Shiraga F,Koide N

更新日期：1988-01-01 00:00:00

abstract：:A case of unilateral disc-shaped cataract with coloboma of the lens is reported. The patient, a 17-year-old girl, had best corrected visual acuity of 0.01 (+ 9 D) in the right eye and 1.2 in the left eye. Exotropia of 10 Hirschberg degrees was found in her right eye. The visual disturbance of that eye was thought to b...

journal_title：Japanese journal of ophthalmology

authors： Kihara Y,Shimomura Y,Omoto T,Fukuda M

更新日期：1988-01-01 00:00:00

abstract：:We reported previously familial hypo-retinol-binding proteinemia in a child who developed keratomalacia during measles infection. In the present study, we characterized serum retinol-binding proteins (RBPs) in the affected family members and compared these RBPs with those in the unaffected family members. Immunoblotti...

journal_title：Japanese journal of ophthalmology

authors： Matsuo T,Matsuo N

更新日期：1988-01-01 00:00:00

abstract：:Inflammation induced by systemic injection of endotoxin can be a good model for endogenous uveitis since ocular inflammation is induced without manipulating the eye. We carried out morphological and biochemical studies in Lewis rats to evaluate the breakdown of the blood-ocular barrier following injection of endotoxin...

journal_title：Japanese journal of ophthalmology

authors： Okumura A,Mochizuki M

更新日期：1988-01-01 00:00:00

abstract：:The protective effect of geraniin (tannin from Geranium thunbergii) against oxidative damage was examined in the mouse ocular lens. Oxidative damage in the lens was induced by diamide, diazene dicarboxylic acid bis (N,N-dimethylamide); diamide oxidized the sulfhydryl groups in both the membrane and cytoplasm but did n...

journal_title：Japanese journal of ophthalmology

authors： Fukaya Y,Nakazawa K,Okuda T,Iwata S

更新日期：1988-01-01 00:00:00

abstract：:The vascular responses to 8 agents, norepinephrine (NE), phenylephrine (PHE), xylazine (XYL), tyramine (TYR), dopamine (DA), 5-hydroxytryptamine (5-HT), prostaglandin F2 alpha (PGF2 alpha) and KCl were examined in human posterior ciliary arteries (HPCAs) which were isolated and perfused with Tyrode's solution gassed w...

journal_title：Japanese journal of ophthalmology

authors： Ohkubo H,Chiba S

更新日期：1988-01-01 00:00:00

abstract：:We evaluated the clinical statistics of a total of 186 patients (101 men and 85 women) with Vogt-Koyanagi-Harada's disease seen in the Uveitis Survey Clinic of the Hokkaido University Hospital during the 18-year period from 1966 to 1983. The annual number of new cases showed some change. More new patients were seen in...

journal_title：Japanese journal of ophthalmology

authors： Ohno S,Minakawa R,Matsuda H

更新日期：1988-01-01 00:00:00

abstract：:Movement of fluorescein and fluorescein glucuronide, a fluorescent metabolite of fluorescein, across the isolated iris-ciliary body of the albino rabbit was determined under short-circuit conditions using a modified Ussing's chamber. The permeabilities of this tissue to these dyes were calculated. The outward permeabi...

journal_title：Japanese journal of ophthalmology

authors： Eguchi S,Araie M,Takase M

更新日期：1987-01-01 00:00:00

abstract：:Full-field electroretinograms (ERGs) provide a basis for establishing the diagnosis of widespread progressive forms of retinitis pigmentosa in early life even at a time when fundus abnormalities visible with the ophthalmoscope are minimal or absent. Patients characteristically show delays in rod or cone b-wave implici...

journal_title：Japanese journal of ophthalmology

authors： Berson EL

更新日期：1987-01-01 00:00:00

abstract：:We reported a case of congenital stationary night blindness (CSNB) who showed Schubert-Bornschein type electroretinogram (ERG) in the right eye and nearly normal ERG in the left eye with absolute glaucoma. From the electrophysiological findings of both eyes and histological findings of the enucleated eye, we concluded...

journal_title：Japanese journal of ophthalmology

authors： Kato M,Aonuma H,Kawamura H,Miura Y,Watanabe I

更新日期：1987-01-01 00:00:00

abstract：:Three cases of medullated nerve fibers of the retina were seen. They had medullated nerve fibers in both the upper and lower quadrants of the temporal retina, whereby the temporal raphe of the retinal nerve fiber layer could be visualized. Some nerve fibers from the upper and lower quadrants crossed each other on the ...

journal_title：Japanese journal of ophthalmology

authors： Sakai T,Sano K,Tsuzuki K,Ueno M,Kawamura Y

更新日期：1987-01-01 00:00:00

abstract：:Prostaglandin D2 (PGD2) and 64E, a derivative of PGs, were tested for their capacity to suppress the growth of retinoblastoma in the nude mouse. Ten million cells of an established cell line of human retinoblastoma, Y-79 cells, were transferred subcutaneously into the nude mouse, and after the transferred cells became...

journal_title：Japanese journal of ophthalmology

authors： Nakamura M,Fujino Y,Mochizuki M,Minoda K,Masuda K

更新日期：1987-01-01 00:00:00

abstract：:This is a clinical and laboratory report on 98 patients with acute viral conjunctivitis who were referred to the Eye Clinic of the Escola Paulista de Medicina of Sao Paulo, Brazil, from February 1983 to February 1984. It was planned with the objective of confirming the importance of adenovirus and enterovirus 70 as et...

journal_title：Japanese journal of ophthalmology

authors： Aoki K,Kawana R,Matsumoto I,Maekawa H,Sawada H,Sakurada N,Nobrega MJ,Del Rey Filho M,Belfort R Jr

更新日期：1987-01-01 00:00:00

abstract：:Spontaneous retinal degeneration of Celestial goldfish was studied histologically and electrophysiologically. Retinal degeneration was divided into three stages. Until the age of 75 days (Stage 0) the retina showed normal histological development and the electroretinograms (ERGs) exhibited dominant b-waves similar to ...

journal_title：Japanese journal of ophthalmology

authors： Sakaue H,Negi A,Matsumura M,Ohkuma M,Honda Y

更新日期：1987-01-01 00:00:00

abstract：:Conventional vitreoretinal surgery for proliferative vitreoretinopathy is unsatisfactory despite numerous innovations over the past 20 years. Silicone oil injections in this series resulted in 70% reattachment of these end-stage cases, but within twelve months over 90% had no useful visual result. The development of a...

journal_title：Japanese journal of ophthalmology

authors： Constable I

更新日期：1987-01-01 00:00:00